4.4.2017 | Ashley Kendal
Prochlorperazine Maleate Oral Uses, Side Effects, Interactions
This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment ). Prochlorperazine belongs to a class of drugs known as phenothiazines.
During pregnancy, this medication should be used only when clearly needed. Babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop symptoms including muscle stiffness or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. Discuss the risks and benefits with your doctor. If you notice any of these symptoms in your newborn anytime during their first month, l the doctor right away.
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In the US.
Laboratory and/or medical tests may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Take this medication by mouth with or without food as directed by your doctor, usually 3 to 4 times daily.
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GENERIC NAME(S): Prochlorperazine Maleate.
Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. This drug may make you dizzy or drowsy or cause blurred vision. Avoid alcoholic beverages.
l your doctor right away if you have any serious side effects, including: mental/mood changes (such as agitation, restlessness), unusual/uncontrolled movements (such as fixed upward stare, neck twisting, tongue movements, muscle spasms ), shaking (tremor), difficulty urinating, enlarged/tender breasts, unusual breast milk production, weakness, easy bleeding/bruising, signs of infection (such as fever, persistent sore throat ), severe stomach / abdominal pain, persistent nausea / vomiting, yellowing eyes / skin.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before taking prochlorperazine, l your doctor or pharmacist if you are allergic to it; or to other phenothiazines (such as chlorpromazine ); or if you have any other allergies.
This medication may interfere with certain laboratory tests (including phenylketonuria, certain pregnancy tests ), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
Do not share this medication with others.
This medication may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). Get medical help right away if you have any of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/ irregular heartbeat, dark urine, signs of kidney problems (such as change in the amount of urine).
Do not double the dose to catch up. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. If you miss a dose, take it as soon as you remember.
Before using this medication, l your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, chronic obstructive pulmonary disease - COPD ), blood / immune system disorders (such as bone marrow depression ), high pressure in the eye ( glaucoma ), heart disease (such as irregular heartbeat ), liver disease, kidney disease, certain brain disorders (such as Reye's syndrome, seizures ), stomach /intestine problems (such as blockage), difficulty urinating (for example, due to enlarged prostate ), pheochromocytoma.
In children, the dosage may also be based on weight. Do not increase your dose or take this medication more often than directed. The dosage is based on your age, medical condition, and response to treatment.
l your doctor right away if you get sunburned or have skin blisters /redness. Limit your time in the sun. This medication may make you more sensitive to the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.
Before having surgery, l your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
This medication is not recommended for use in children younger than 2 years or in children going through surgery.
Older adults may be more sensitive to the side effects of this drug, especially low blood pressure, constipation, urinary problems, and nerve/muscle problems.
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Some products that may interact with this drug include: cabergoline, dofetilide, metoclopramide.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else.
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If any of these effects persist or worsen, l your doctor or pharmacist promptly. Drowsiness, dizziness, lightheadedness, blurred vision, constipation, or dry mouth may occur.
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l your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone ), alcohol, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine ), or antihistamines (such as cetirizine, diphenhydramine ).
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To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.
Get medical help right away if you have any very serious side effects, including: seizures.
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2016 First Databank, Inc. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised November 2016. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. US residents can call their local poison control center at. Symptoms of overdose may include: mental/mood changes (such as restlessness, agitation), severe drowsiness, seizures, irregular heartbeat. Otherwise, call a poison control center right away. Canada residents can call a provincial poison control center.
This document does not contain all possible drug interactions. Drug interactions may change how your medications work or increase your risk for serious side effects. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.
Many people using this medication do not have serious side effects. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
However, similar drugs pass into breast milk. Consult your doctor before breast-feeding. It is unknown if prochlorperazine passes into breast milk.
l your doctor if your condition persists or worsens.
You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Call your doctor for medical advice about side effects.
Children with short-term illnesses (such as a viral infection, dehydration ) may be more sensitive to the side effects of this drug, especially nerve/muscle problems.
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This medication may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. If you overheat, quickly look for a place to cool down and rest. Get medical help right away if you have a fever that does not go away, mental/mood changes, headache, or dizziness.
Do not store in the bathroom. Store at room temperature away from light and moisture. Keep all medications away from children and pets.
Discuss the risks and benefits of this medication with the doctor. This medication is not approved for the treatment of dementia-related behavior problems. There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/ irregular heartbeat, pneumonia ) when this medication is used by older adults with dementia.
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A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat), severe dizziness, trouble breathing.
You may report side effects to Health Canada at. In Canada - Call your doctor for medical advice about side effects.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Ask your pharmacist about using those products safely. Check the labels on all your medicines (such as allergy or cough -and-cold products) because they may contain ingredients that cause drowsiness.Prochlorperazine