8.25.2017 | Nicholas Babcock
Diastat (diazepam rectal gel)
Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Medications other than those listed above may interact with this medication. l your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also l them about any supplements you take.
It can be harmful for people to use this medication if their doctor has not prescribed it. Do not give this medication to anyone else, even if they have the same symptoms as you do.
Treatment with diazepam rectal gel should be given no more than every 5 days, and no more than 5 times per month.
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Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks.
If a single dose does not adequay treat the seizure, your doctor may wish to prescribe 2 doses of diazepam rectal gel. The second dose may be given 4 to 12 hours after the first dose if seizures continue or are known to recur, or if the patient is known to have seizures that are especially resistant to treatment.
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:.
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These factors may affect how you should use this medication. Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health.
Diazepam rectal gel should not be used by women who are breast-feeding. Breast-feeding: Diazepam passes into breast milk.
Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Terms and conditions of use. All material MediResource Inc. Source: www.medbroadcast.com/drug/getdrug/Diastat. The contents herein are for informational purposes only. 1996 – 2017.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Diazepam rectal gel usually starts controlling seizures 5 to 15 minutes after it is used. It works by slowing down the nerves in the brain (i.e., the central nervous system). This medication is used to treat those who experience an increase in their seizure frequency at home, in hospitals, in emergency units, or in residential institutions.
The dose of diazepam rectal gel is individualized according to weight and age.
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It is used for the intermittent treatment of severe seizures (also known as recurrent, serial, cluster, or crescendo seizures) that occur for certain people even though they take regular doses of medications to treat epilepsy. Diazepam belongs to the class of medications called benzodiazepines.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
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For ages 12 and over, the recommended dose is 0.2 mg per kilogram. For children 6 to 11 years of age, the dose is 0.3 mg per kilogram. For children 2 to 4 years of age, the dose is 0.5 mg per kilogram of body weight.
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Ask your pharmacist how to dispose of medications that are no longer needed or have expired. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage.
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Nonmedicinal ingredients: benzoic acid, benzyl alcohol (1.5%), ethyl alcohol (10%), hydroxypropyl methylcellulose, propylene glycol, sodium benzoate, and water. Each rectal delivery system of clear to slightly yellow, non-sterile gel, with a pH between 6.5 to 7.2, contains diazepam 5 mg/mL.
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Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. Do not stop using this medication without consulting your doctor. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. As well, some forms of this medication may not be used for all of the conditions discussed here.
Children: The safety and effectiveness of diazepam rectal gel for children under 2 years of age have not been established.
Diazepam should not be used by anyone who:
If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Many medications can cause side effects. The side effects listed below are not experienced by everyone who takes this medication. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
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There may be an interaction between diazepam rectal gel and any of the following:
Since the dose of diazepam rectal gel is available in fixed unit doses of 5 mg, 10 mg, 15 mg, and 20 mg only, the prescribed dose is obtained by rounding upward to the next available dose. For seniors, it is recommended that the dosage be rounded downwards.
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Stop taking the medication and seek immediate medical attention if any of the following occur:
Store the syringe away from children. Use the preloaded diazepam rectal gel syringe exactly as prescribed by your doctor and according to package directions.
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Seniors: The dose of diazepam rectal gel may need to be decreased for those over 60 years of age to avoid over-sedation and impaired coordination.
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Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
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Drowsiness/reduced alertness: Because diazepam causes drowsiness and sedation, do not engage in activities requiring mental alertness such as driving a car or operating machinery until the sedating effects of this medication have worn off. Alcohol can increase the drowsiness effects and should be avoided.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Liver function: This medication should not be used by anyone with reduced liver function unless the benefits outweigh the risks.
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